Endocrine Abstracts

Various types of human germ cell tumors (GCTs) can be found, referred to as type I, II and III. The type I are the teratomas and yolk sac tumors of neonates and infants. No genomic aberrations have been identified in teratomas, while yolk sac tumors show chromosomal imbalances related to chromosomes 1, 6 and 20. Type II GCTs are the seminomas and nonseminomas, derived from carcinoma in situ (CIS)/intratubular germ cell neoplasia unclassified (ITGCNU). CIS/ITGCNU and sem...

Cushing’s syndrome (CS) during pregnancy is a rare metabolic condition with only a few cases reported in the literature. Misdiagnosis of CS is common because of the overlapping features of fatigue, weight gain, striae, and emotional changes that occur during normal pregnancy. The clinical presentation together with laboratory and imaging findings help to make a diagnosis. However, changes in maternal hormones and their binding proteins complicate assessment of the normal ...